Genetic Characterization of Peste des Petits Ruminants Virus, Sierra Leone
نویسندگان
چکیده
6. Wielders CC, van Binnendijk RS, Snijders BE, Tipples GA, Cremer J, Fanoy E, et al. Mumps epidemic in orthodox religious low-vaccination communities in the Netherlands and Canada, 2007 to 2009. Euro Surveill. 2011;16:pii=19989. 7. Whelan J, van Binnendijk R, Greenland K, Fanoy E, Khargi M, Yap K, et al. Ongoing mumps outbreak in a student population with high vaccination coverage, Netherlands, 2010. Euro Surveill. 2010;13:15. 8. Quinlisk MP. Mumps control today. J Infect Dis. 2010;202:655–6. doi:10.1086/655395
منابع مشابه
Complete Genome Sequence of a Lineage II Peste des Petits Ruminants Virus from Sierra Leone
The complete genome sequence of a peste des petits ruminants virus (PPRV) from goat samples collected in Sierra Leone in 2011 is reported here. The genome shows a higher nucleotide sequence identity (98.9%) with a lineage II PPRV from Senegal than to PPRVs from neighboring Liberia and Ivory Coast.
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Small ruminants infected with peste des petits ruminants virus exhibit lesions typical of epithelial infection and necrosis. However, the only established host receptor for this virus is the immune cell marker signaling lymphocyte activation molecule (SLAM). We have confirmed that the ovine Nectin-4 protein, when overexpressed in epithelial cells, permits efficient replication of PPRV. Furtherm...
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عنوان ژورنال:
دوره 18 شماره
صفحات -
تاریخ انتشار 2012